糖尿病与癌症相关联的机制研究

被引：13

作者：

吴文君 ^{[1
]}

朱大龙 ^{[2
]}

机构：

[1] 南京医科大学附属无锡市人民医院内分泌科

[2] 不详

来源：

中国肿瘤临床 | 2013年 / 40卷 / 11期

关键词：

糖尿病; 癌症; 关联机制;

D O I：

暂无

中图分类号：

R587.2 [糖尿病性昏迷及其他并发症]; R730.2 [肿瘤病理学、病因学];

学科分类号：

摘要：

糖尿病与癌症是对公众健康产生严重影响的常见疾病。流行病学证据表明糖尿病患者某些癌症的发生及死亡风险增加,主要包括胰腺癌、肝癌、结直肠癌、肾癌、膀胱癌、女性乳腺癌及子宫内膜癌等。糖尿病与癌症之间可能存在直接和间接的关联,两者间直接的生物学机制可能是高胰岛素血症、高血糖和慢性炎症,两者存在的共同危险因素包括年龄、性别、种族、肥胖、饮食、体育锻炼、吸烟和酒精。本文综述了糖尿病与癌症相关联机制的研究证据。

引用

页码：682 / 684

页数：3

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