急性冠脉综合征患者血清脂联素与高敏C反应蛋白的关系

被引：6

作者：

罗素新 ^{[1
]}

雷寒 ^{[1
]}

马康华 ^{[1
]}

柳青 ^{[2
]}

机构：

[1] 重庆医科大学附属第一医院心内科

[2] 重庆医科大学附属第一医院临床研究中心

来源：

重庆医科大学学报 | 2005年 / 06期

关键词：

急性冠状动脉综合征; 脂联素; 高敏C反应蛋白;

D O I：

10.13406/j.cnki.cyxb.2005.06.005

中图分类号：

R541.4 [冠状动脉（粥样）硬化性心脏病（冠心病）];

学科分类号：

1002 ; 100201 ;

摘要：

目的:探讨急性冠状动脉综合征(ACS)患者血清脂联素与高敏C反应蛋白(hsCRP)的关系。方法:收集行冠状动脉造影术的冠心病患者90例,其中急性心肌梗死(AMI)41例,不稳定性心绞痛(UAP)27例;稳定性心绞痛(SAP)22例,健康对照组20例。采用酶联免疫吸附法(ELISA)测定血清脂联素,采用免疫散射比浊法测定hsCRP。结果:ACS组血清脂联素浓度显著低于SAP组(P<0．05)和对照组(P<0．01),hsCRP浓度显著高于SAP组(P<0．05)和对照组(P<0．01),且ACS组血清脂联素与hsCRP呈负相关(r=-0．33,P<0．05)。结论:脂联素具有抗炎、抗动脉粥样硬化的保护作用,对ACS的发生和发展有一定的预测价值。

引用

页码：791 / 793

页数：3

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