流行性感冒防控新策略研究进展

被引：5

作者：

徐鹏卫 ^{[1
]}

代克强 ^{[2
]}

卢建国 ^{[3
]}

吴卫东 ^{[1
]}

机构：

[1] 新乡医学院公共卫生学院

[2] 新乡医学院第一临床学院

[3] 新乡医学院第一附属医院胸外二科

来源：

新乡医学院学报 | 2017年 / 34卷 / 11期

关键词：

流行性感冒病毒; 疫苗; 抗病毒药物; 防控策略;

D O I：

暂无

中图分类号：

R511.7 [流行性感冒];

学科分类号：

100401 [流行病与卫生统计学];

摘要：

流行性感冒是由流行性感冒病毒引起的可造成大规模流行的急性呼吸道传染病,具有较高的发病率和致死率,是长期以来威胁人类健康的主要传染病之一。当前的疫苗、抗病毒药物可用于控制流行性感冒,但均存在一定的局限性和弊端,如流行性感冒疫苗的保护能力有限,且每年均需随病毒的变异而更新;抗病毒药物可能导致快速而广泛的耐药性产生。因此,研究更为安全、高效的流行性感冒防控手段仍是当前的科研热点之一,本文针对以病毒或宿主细胞为靶点的抗流行性感冒新策略进行了综述。

引用

收藏

页码：955 / 959

页数：5

相关论文

共 17 条

[1]

Investigating the efficacy of pamidronate, a chemical inhibitor of farnesyl pyrophosphate synthase, in the inhibition of influenza virus infection in vitro and in vivo [J].

Tan, Kai Sen ;

Ng, Wai Chii ;

Seet, Ju Ee ;

Olfat, Farzad ;

Engelward, Bevin P. ;

Chow, Vincent T. K. .

MOLECULAR MEDICINE REPORTS, 2014, 9 (01) :51-56

[2]

How academic labs can approach the drug discovery process as a way to synergize with big pharma [J].

Loregian, Arianna ;

Palu, Giorgio .

TRENDS IN MICROBIOLOGY, 2013, 21 (06) :261-264

[3]

Lipidomic Profiling of Influenza Infection Identifies Mediators that Induce and Resolve Inflammation [J].

Tam, Vincent C. ;

Quehenberger, Oswald ;

Oshansky, Christine M. ;

Suen, Rosa ;

Armando, Aaron M. ;

Treuting, Piper M. ;

Thomas, Paul G. ;

Dennis, Edward A. ;

Aderem, Alan .

CELL, 2013, 154 (01) :213-227

[4]

Lessons from Lipids in the Fight against Influenza [J].

Garcia-Sastre, Adolfo .

CELL, 2013, 154 (01) :22-23

[5]

The Lipid Mediator Protectin D1 Inhibits Influenza Virus Replication and Improves Severe Influenza [J].

Morita, Masayuki ;

Kuba, Keiji ;

Ichikawa, Akihiko ;

Nakayama, Mizuho ;

Katahira, Jun ;

Iwamoto, Ryo ;

Watanebe, Tokiko ;

Sakabe, Saori ;

Daidoji, Tomo ;

Nakamura, Shota ;

Kadowaki, Ayumi ;

Ohto, Takayo ;

Nakanishi, Hiroki ;

Taguchi, Ryo ;

Nakaya, Takaaki ;

Murakami, Makoto ;

Yoneda, Yoshihiro ;

Arai, Hiroyuki ;

Kawaoka, Yoshihiro ;

Penninger, Josef M. ;

Arita, Makoto ;

Imai, Yumiko .

CELL, 2013, 153 (01) :112-125

[6]

Combination of MEK inhibitors and oseltamivir leads to synergistic antiviral effects after influenza A virus infection in vitro [J].

Haasbach, Emanuel ;

Hartmayer, Carmen ;

Planz, Oliver .

ANTIVIRAL RESEARCH, 2013, 98 (02) :319-324

[7]

Influenza virus resistance to neuraminidase inhibitors [J].

Samson, Melanie ;

Pizzorno, Andres ;

Abed, Yacine ;

Boivin, Guy .

ANTIVIRAL RESEARCH, 2013, 98 (02) :174-185

[8]

Monomeric Nucleoprotein of Influenza A Virus [J].

Chenavas, Sylvie ;

Estrozi, Leandro F. ;

Slama-Schwok, Anny ;

Delmas, Bernard ;

Di Primo, Carmelo ;

Baudin, Florence ;

Li, Xinping ;

Crepin, Thibaut ;

Ruigrok, Rob W. H. .

PLOS PATHOGENS, 2013, 9 (03)

[9]

Highly Conserved Protective Epitopes on Influenza B Viruses [J].

Dreyfus, Cyrille ;

Laursen, Nick S. ;

Kwaks, Ted ;

Zuijdgeest, David ;

Khayat, Reza ;

Ekiert, Damian C. ;

Lee, Jeong Hyun ;

Metlagel, Zoltan ;

Bujny, Miriam V. ;

Jongeneelen, Mandy ;

van der Vlugt, Remko ;

Lamrani, Mohammed ;

Korse, Hans J. W. M. ;

Geelen, Eric ;

Sahin, Ozcan ;

Sieuwerts, Martijn ;

Brakenhoff, Just P. J. ;

Vogels, Ronald ;

Li, Olive T. W. ;

Poon, Leo L. M. ;

Peiris, Malik ;

Koudstaal, Wouter ;

Ward, Andrew B. ;

Wilson, Ian A. ;

Goudsmit, Jaap ;

Friesen, Robert H. E. .

SCIENCE, 2012, 337 (6100) :1343-1348

[10]

Recent Advances in Neuraminidase Inhibitor Development as Anti-influenza Drugs [J].

Feng, Enguang ;

Ye, Deju ;

Li, Jian ;

Zhang, Dengyou ;

Wang, Jinfang ;

Zhao, Fei ;

Hilgenfeld, Rolf ;

Zheng, Mingyue ;

Jiang, Hualiang ;

Liu, Hong .

CHEMMEDCHEM, 2012, 7 (09) :1527-1536