TOLL样受体介导信号通路与类风湿关节炎关系的研究进展

被引：11

作者：

晋小荣

朱苗苗

高永翔

张宇宏

机构：

[1] 成都中医药大学

来源：

湖南中医杂志 | 2017年 / 33卷 / 10期

关键词：

TLRs; 信号通路; 类风湿关节炎; 综述,学术性;

D O I：

10.16808/j.cnki.issn1003-7705.2017.10.087

中图分类号：

R593.22 [类风湿性关节炎];

学科分类号：

100201 [内科学];

摘要：

<正>类风湿关节炎(Rheumatoid Arthritis,RA)是一种常见的以关节滑膜慢性炎症及血管翳形成为病理特征的慢性自身免疫功能障碍性疾病,临床表现以多关节疼痛、肿胀及活动障碍为主,常伴有关节外多系统的损伤,其病因未明,发病机制尚未完全清楚。机体在天然免疫过程中识别特定病原体相关的分子模式(PAMPs)需要依赖于一组模式识别受体(PRRs),作为

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页码：193 / 195

页数：3

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