巨噬细胞表型与肾损伤修复的研究进展

被引:3
作者
耿燕秋 [1 ,2 ,3 ]
张利 [1 ,2 ]
陈香美 [1 ,2 ]
机构
[1] 解放军总医院解放军医学院
[2] 肾脏疾病国家重点实验室
[3] 武警总医院肾内科
关键词
巨噬细胞; 活化; 肾脏; 损伤;
D O I
10.14010/j.cnki.wjyx.2014.04.003
中图分类号
R392.12 [免疫细胞生物学];
学科分类号
摘要
<正>单核巨噬细胞系统在免疫介导的肾病和宿主防御中发挥着重要作用,它与组织损伤的诱导、纤维化及损伤后修复密切相关,并决定着免疫反应的结局,表明巨噬细胞具有异质性。为此笔者对近年来关于肾损伤后的免疫反应及不同表型巨噬细胞在肾损伤和修复过程中发挥的作用研究。1巨噬细胞起源和异质性巨噬细胞是机体内重要的吞噬和抗原提呈细胞,也是造血系统中最古老的细胞类型,哺乳动物的
引用
收藏
页码:399 / 402
页数:4
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