肠道益生菌对非酒精性脂肪肝的影响

被引：29

作者：

杨文

王玉柱

于晓红

杨志健

机构：

[1] 海军总医院干部病房消化内科

来源：

胃肠病学和肝病学杂志 | 2014年 / 23卷 / 02期

关键词：

益生菌; 非酒精性脂肪肝;

D O I：

暂无

中图分类号：

R575.5 [肝代谢障碍];

学科分类号：

100201 [内科学];

摘要：

目的探讨肠道菌群与非酒精性脂肪肝(NAFLD)的关系。方法对53例服用肠道益生菌的NAFLD患者和56例对照组患者进行服药前后肝脏的超声检查,抽血查血肌酐、尿素氮、总胆固醇、三酰甘油、空腹血糖,并同时对年龄和体质量指数(BMI)进行统计。结果服药前两组各项指标比较,差异无统计学意义(P>0.05)。服药后肠道益生菌组和对照组比较,脂肪肝消退数明显增加,差异有统计学意义(P<0.05)。服药前后两组比较,肠道益生菌组服药后较服药前脂肪肝消退数明显增加,差异有统计学意义(P<0.01);而对照组各项指标比较,差异均无统计学意义(P>0.05)。两组服药前后各种观察指标差值的比较,脂肪肝消退、中度脂肪肝减少数、总胆固醇、三酰甘油和尿素氮下降在肠道益生菌组差异有统计学意义(P<0.05、P<0.01)。结论口服益生菌可以降低NAFLD的发生,益生菌可能具有预防和治疗NAFLD的作用。

引用

收藏

页码：227 / 229

页数：3

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