二茂铁功能化FeO/碳纳米管/壳聚糖复合膜葡萄糖生物传感电极的研究

被引：2

作者：

彭花萍 ^{[1
]}

查代君 ^{[2
]}

黄郑隽 ^{[1
]}

陈伟 ^{[1
]}

刘爱林 ^{[1
]}

林新华 ^{[1
]}

机构：

[1] 福建医科大学药学院药物分析系

[2] 南昌大学高等研究院

来源：

电化学 | 2014年 / 01期

关键词：

二茂铁修饰Fe3O4; 碳纳米管; 壳聚糖; 葡萄糖氧化酶; 生物传感器;

D O I：

10.13208/j.electrochem.121108

中图分类号：

O657.1 [电化学分析法];

学科分类号：

摘要：

采用交联法制备了羧基二茂铁功能化Fe3O4纳米粒子(FMC-AFNPs)复合材料,并将该复合纳米材料与多壁碳纳米管(MWNTs)、壳聚糖(CS)及葡萄糖氧化酶(GOD)混合修饰于自制的磁性玻碳基底(MGC)表面,制备了GOD/FMC-AFNPs/MWNTs/CS复合膜生物传感器电极.实验结果表明,FMC-AFNPs复合材料有效地克服了二茂铁在电极表面的泄漏,且FMC-AFNPs/MWNTs/CS复合膜良好的生物兼容性较大地改善了固定化GOD的生物活性.MWNTs具有良好的导电性和大比表面积,在修饰膜内可作为电子传递"导线",极大地促进电极的电子传递速率,提高电极的电催化活性和灵敏度.该电极的葡萄糖检测的线性范围为1.0×10-5～6.0×10-3mol·L-1,检测限为3.2×10-6mmol·L-1(S/N=3),表观米氏常数为5.03·10-3mmol·L-1,且有较好的稳定性和重现性.

引用

页码：33 / 38

页数：6

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