褪黑素抗乳腺癌作用及其机制的研究进展

被引：3

作者：

王华

胡冰

机构：

[1] 安徽医科大学附属省立医院肿瘤科

来源：

中国药理学通报 | 2008年 / 02期

关键词：

褪黑素; 乳腺癌; 机制;

D O I：

暂无

中图分类号：

R737.9 [乳腺肿瘤];

学科分类号：

100214 ;

摘要：

褪黑素(melatonin,MT)是主要由松果腺分泌的生物活性物质。近年来大量文献表明MT能抑制乳腺癌的发生,其中有多种作用机制参与;MT可以抑制雌激素受体基因表达,调节雌激素信号转导通路,抑制细胞增殖和侵袭等等,因此提高内源性MT的生成或给予MT治疗可能对乳腺癌病人有益。该文综述了MT抗乳腺癌的作用机制及其可能应用。

引用

页码：144 / 148

页数：5

共 18 条

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