中潜伏期体感诱发电位预测重症脑卒中患者预后的应用价值

被引:10
作者
张艳
宿英英
肖淑英
机构
[1] 首都医科大学宣武医院神经内科
关键词
卒中; 诱发电位,躯体感觉; 格拉斯哥昏迷量表; 预后;
D O I
暂无
中图分类号
R743.3 [急性脑血管疾病(中风)];
学科分类号
1002 ;
摘要
目的探讨中潜伏期体感诱发电位(middle-latency somatosensory evoked potentials,MLSEP)预测急性重症脑卒中患者预后的应用价值。方法对70例症状出现7 d内的重症脑卒中患者行格拉斯哥昏迷评分(Glasgow Coma Scale,GCS)、短潜伏期体感诱发电位(short-latencysomatosensory evoked potentials,SLSEP)和MLSEP检测,6个月后采用改良Rankin评分和生存与死亡两个预后标准进行预后评估。健康对照组20名行SLSEP和MLSEP检测。统计学分析MLSEP、SLSEP和GSC与预后的一致性及预测的准确性。结果健康对照组均记录到双侧N20、N35和N60,脑卒中组患者MLSEP波形有缺失,而且病灶侧MLSEP各波消失比例明显高于对侧。双侧N60消失与预后不良(Kappa=0.828,P<0.01)和死亡(Kappa=0.686,P<0.01)的一致性均最好。预测准确性分析显示:病灶侧N60消失预测不良预后和死亡的敏感性高达100%,较病灶侧N20消失的敏感性(85.7%)提高了14.3%;双侧N60消失预测预后不良的特异性为100%,与双侧N20消失一致;但预测死亡的特异性为82.9%,不如双侧N20消失(97.1%)。结论 MLSEP可反映脑损伤程度,预测预后不良的敏感性高于SLSEP,建议将MLSEP和SLSEP联合用于重症脑损伤后的评估与预后的预测。
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