脊髓损伤后继发中枢性疼痛的药物治疗研究进展

被引:2
作者
王昕辉
易红蕾
朱佳丽
熊源长
机构
[1] 第二军医大学附属上海长海医院麻醉科
关键词
D O I
暂无
中图分类号
R651.2 [脊髓];
学科分类号
1002 ; 100210 ;
摘要
<正>中枢性疼痛(central pain,CP)是指中枢神经系统的损伤或功能障碍引起的疼痛,属于神经病理性疼痛。国际疼痛协会特别强调其原因是中枢神经系统内的原发过程,其最常见的病因是脊髓损伤(spinal cord injury,SCI)。据报道SCI后CP的发生率为34%~94%。由于疼痛顽固难以治疗,
引用
收藏
页码:1270 / 1273
相关论文
共 24 条
[1]   脊髓损伤后中枢性疼痛的实验模型和机制研究进展 [J].
谢永刚 ;
张小洺 ;
姚尚龙 .
国际麻醉学与复苏杂志, 2006, (06) :357-360
[2]   鼠坐骨神经损伤后雪旺细胞增殖规律的免疫组织化学观察 [J].
赵富强 ;
姜保国 ;
张培训 ;
张宏波 .
中华外科杂志, 2006, (04) :268-270
[3]   Targeting Neuroprotection as an Alternative Approach to Preventing and Treating Neuropathic Pain [J].
Bordet, Thierry ;
Pruss, Rebecca M. .
NEUROTHERAPEUTICS, 2009, 6 (04) :648-662
[4]  
Neuropathic pain in spinal cord injury: Identification, classification, evaluation[J] . P. Calmels,G. Mick,B. Perrouin-Verbe,M. Ventura.Annals of Physical and Rehabilitation Medicine . 2009 (2)
[5]  
Chronic neuropathic pain in patients with spinal cord injury. What is the efficacy of regional interventions? Sympathetic blocks, nerve blocks and intrathecal drugs[J] . D. Bensmail,C. Ecoffey,M. Ventura,T. Albert.Annals of Physical and Rehabilitation Medicine . 2009 (2)
[6]  
Gabapentin and pregabalin ameliorate mechanical hypersensitivity after spinal cord injury in mice[J] . Mitsuo Tanabe,Koto Ono,Motoko Honda,Hideki Ono.European Journal of Pharmacology . 2009 (1)
[7]  
Peripheral and central sensitization in remote spinal cord regions contribute to central neuropathic pain after spinal cord injury[J] . Susan M. Carlton,Junhui Du,Huai Yu Tan,Olivera Nesic,Gregory L. Hargett,Anne C. Bopp,Ammar Yamani,Qing Lin,William D. Willis,Claire E. Hulsebosch.Pain . 2009 (1)
[8]  
Tramadol in Neuropathic Pain After Spinal Cord Injury: A Randomized, Double-blind, Placebo-controlled Trial[J] . Cecilia Norrbrink,Thomas Lundeberg.The Clinical Journal of Pain . 2009 (3)
[9]  
Efficacy of pregabalin and gabapentin for neuropathic pain in spinal-cord injury: an evidence-based evaluation of the literature[J] . Thrasivoulos G. Tzellos,Georgios Papazisis,Ekaterini Amaniti,Dimitrios Kouvelas.European Journal of Clinical Pharmacology . 2008 (9)
[10]   Pregabalin as a neuroprotector after spinal cord injury in rats [J].
Ha, Kee-Yong ;
Kim, Young-Hoon ;
Rhyu, Kee-Won ;
Kwon, Soon-Eok .
EUROPEAN SPINE JOURNAL, 2008, 17 (06) :864-872