非酒精性脂肪性肝病与肝癌关系研究进展

被引:9
作者
郑刚
机构
[1] 荆门市第一人民医院普外科
关键词
肝细胞癌; 非酒精性脂肪性肝病; 糖尿病; 肥胖;
D O I
暂无
中图分类号
R735.7 [肝肿瘤]; R575.5 [肝代谢障碍];
学科分类号
100112 [医学生物化学与分子生物学]; 100201 [内科学];
摘要
随着生活水平提高,生活习惯与饮食结构的改变,非酒精性脂肪性肝病的发病率在不断增加。非酒精性脂肪性肝病包括一系列的疾病谱:单纯性脂肪肝、脂肪性肝炎、脂肪性肝纤维化及脂肪性肝硬化。肝细胞癌是脂肪性肝硬化的严重后果。因此,非酒精性脂肪性肝病与肝细胞癌之间存在着重要关系。本文就非酒精性脂肪性肝病与肝细胞癌关系的研究进展总结如下。
引用
收藏
页码:216 / 220
页数:5
相关论文
共 21 条
[1]
Treatment of non-alcoholic fatty liver disease with focus on emerging drugs [J].
Marchesini, Giulio ;
Moscatiello, Simona ;
Agostini, Federica ;
Villanova, Nicola ;
Festi, Davide .
EXPERT OPINION ON EMERGING DRUGS, 2011, 16 (01) :121-136
[2]
Long-Term Follow-Up of Patients With Nonalcoholic Fatty Liver [J].
Rafiq, Nila ;
Bai, Chunhong ;
Fang, Yun ;
Srishord, Manirath ;
McCullough, Arthur ;
Gramlich, Terry ;
Younossi, Zobair M. .
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 2009, 7 (02) :234-238
[3]
Epidemiology and Natural History of Non-Alcoholic Steatohepatitis [J].
Argo, Curtis K. ;
Caldwell, Stephen H. .
CLINICS IN LIVER DISEASE, 2009, 13 (04) :511-+
[4]
NASH and HCC [J].
Page, John M. ;
Harrison, Stephen A. .
CLINICS IN LIVER DISEASE, 2009, 13 (04) :631-+
[5]
Short-term 20-mg atorvastatin therapy reduces key inflammatory factors including c-Jun N-terminal kinase and dendritic cells and matrix metalloproteinase expression in human abdominal aortic aneurysmal wall [J].
Kajimoto, Kan ;
Miyauchi, Katsumi ;
Kasai, Takatoshi ;
Shimada, Kazunori ;
Kojima, Yuko ;
Shimada, Akie ;
Niinami, Hiroshi ;
Amano, Atsushi ;
Daida, Hiroyuki .
ATHEROSCLEROSIS, 2009, 206 (02) :505-511
[6]
Statins Are Associated With a Reduced Risk of Hepatocellular Carcinoma in a Large Cohort of Patients With Diabetes [J].
El-Serag, Hashem B. ;
Johnson, Michael L. ;
Hachem, Christine ;
Morgana, Robert O. .
GASTROENTEROLOGY, 2009, 136 (05) :1601-1608
[7]
Hepatocellular carcinoma in patients with nonalcoholic steatohepatitis [J].
Etsuko Hashimoto ;
Satoru Yatsuji ;
Maki Tobari ;
Makiko Taniai ;
Nobuyuki Torii ;
Katsutoshi Tokushige ;
Keiko Shiratori .
Journal of Gastroenterology, 2009, 44 :89-95
[8]
Diagnosis and therapy of nonalcoholic steatohepatitis [J].
Torres, Dawn M. ;
Harrison, Stephen A. .
GASTROENTEROLOGY, 2008, 134 (06) :1682-1698
[9]
<ce:link locator="fx1"/> Liver Iron; HFE Gene Mutations; and Hepatocellular Carcinoma Occurrence in Patients With Cirrhosis.[J].Pierre Nahon;Angela Sutton;Pierre Rufat;Marianne Ziol;Gabriel Thabut;Pierre–Olivier Schischmanoff;Dominique Vidaud;Nathalie Charnaux;Philippe Couvert;Nathalie Ganne–Carrie;Jean–Claude Trinchet;Liliane Gattegno;Michel Beaugrand.Gastroenterology.2008, 1
[10]
Activation and dysregulation of the unfolded protein response in nonalcoholic fatty liver disease [J].
Puri, Puneet ;
Mirshahi, Faridoddin ;
Cheung, Onpan ;
Natarajan, Ramesh ;
Maher, James W. ;
Kellum, John M. ;
Sanyal, Arun J. .
GASTROENTEROLOGY, 2008, 134 (02) :568-576