超氧化物歧化酶的生物学效应和在血管性疾病中的作用

被引：18

作者：

陈珊

程熠

刘全

机构：

[1] 吉林大学白求恩第一医院心血管诊治中心

来源：

中国老年学杂志 | 2013年 / 33卷 / 04期

关键词：

超氧化物歧化酶; SOD; 超氧阴离子; 心血管疾病; 动脉粥样硬化;

D O I：

暂无

中图分类号：

R543.5 [动脉疾病];

学科分类号：

1002 ; 100201 ;

摘要：

<正>血管超氧阴离子(O2)是正常细胞新陈代谢产生的一个副产品,被认为是其他一些活性氧簇(ROS)(包括H2O2和ONOO-)的始祖。在血管中,O2水平的改变可调节血管张力、基因表达、炎症反映、细胞生长、信号传导及细胞凋亡。

引用

页码：981 / 984

页数：4

共 16 条

[1]

NADPH Oxidases: Functions and Pathologies in the Vasculature[J] . Bernard Lassègue,Kathy K. Griendling.Arteriosclerosis, Thrombosis, and Vascular Biology . 2010 (4)

[2] Cytokine activation of nuclear factor κB in vascular smooth muscle cells requires signaling endosomes containing Nox1 and ClC-3 [J].

Miller, Francis J., Jr. ;

Filali, Mohammed ;

Huss, Gina J. ;

Stanic, Bojana ;

Chamseddine, Ali ;

Barna, Thomas J. ;

Lamb, Fred S. .

CIRCULATION RESEARCH, 2007, 101 (07) :663-671

[3] Basic mechanisms of oxidative stress and reactive oxygen species in cardiovascular injury [J].

Papaharalambus, Christopher A. ;

Griendling, Kathy K. .

TRENDS IN CARDIOVASCULAR MEDICINE, 2007, 17 (02) :48-54

[4] Extracellular superoxide dismutase accelerates endothelial recovery and inhibits in-stent restenosis in stented atherosclerotic watanabe heritable hyperlipidemic rabbit aorta [J].

Brasen, Jan Hinrich ;

Leppanen, Olli ;

Inkala, Matias ;

Heikura, Tommi ;

Levin, Max ;

Ahrens, Fabian ;

Rutanen, Juha ;

Pietsch, Hubertus ;

Bergqvist, David ;

Levonen, Anna-Liisa ;

Basu, Samar ;

Zeller, Thomas ;

Kloppel, Gunter ;

Laukkanen, Mikko O. ;

Yla-Herttuala, Seppo .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2007, 50 (23) :2249-2253

[5] Mitochondrial dysfunction in atherosclerosis [J].

Madamanchi, Nageswara R. ;

Runge, Marschall S. .

CIRCULATION RESEARCH, 2007, 100 (04) :460-473

[6]

Vascular NADPH oxidases as drug targets for novel antioxidant strategies[J] . Tomasz J. Guzik,David G. Harrison.Drug Discovery Today . 2006 (11)

[7] Gene therapy for vascular disease [J].

Heistad, Donald D. .

VASCULAR PHARMACOLOGY, 2006, 45 (05) :331-333

[8]

Redox Redux: Revisiting PTPs and the Control of Cell Signaling[J] . Nicholas K. Tonks.Cell . 2005 (5)

[9]

Mitochondria, Oxidants, and Aging[J] . Robert S. Balaban,Shino Nemoto,Toren Finkel.Cell . 2005 (4)

[10] Extracellular superoxide dismutase overexpression reduces cuff-induced arterial neointimal formation [J].

Ozumi, K ;

Tasaki, H ;

Takatsu, H ;

Nakata, S ;

Morishita, T ;

Koide, S ;

Yamashita, K ;

Tsutsui, M ;

Okazaki, M ;

Sasaguri, Y ;

Adachi, T ;

Nakashima, Y .

ATHEROSCLEROSIS, 2005, 181 (01) :55-62

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