米诺环素治疗脊髓损伤的研究进展

[11] Minocycline blocks ni-tric oxide-induced neurotoxicity by inhibition p38 MAP kinasein rat cerebellar granule neurons. LIN S,ZHANG Y,DODEL R,et al. Neuroscience Letters . 2001

[12] M inocyc line inh ib itscaspase-independent and-dependentm itochondrial cell deathpathways in models of Huntington’s disease. WANG X,ZHU S,DROZDA M,et al. Proceedings of the National Academy of Sciences of the United States of America . 2003

[13] M inocyc line in-h ib its contusion-triggered m itochondrial cytochrom e c releaseand m itigates functional defic its after sp inal cord in jury. TENG Y D,CHO I H,ONAR IO R C,et al. Proceedings of the National Academy of Sciences of the United States of America . 2004

[14] M inocy-c line inh ib its cytochrom e c release and delays progression ofamyotroph ic lateral sc lerosis in m ice. ZHU S,STAVROVSKAYA I G,DROZDA M,et al. Nature . 2002

[15] M inocy-c line,a tetracyc line derivative,is neuroprotective against exc i-totoxic ity by inh ib iting activation and proliferation of m icroglia. TIKKA T,FIEB ICH B L,GOLDSTEINS G,et al. J Neurosc i . 2001

[16] Mi-nocycline inhibits caspase activation and reactivation,increa-ses the ratio of XIAP to smac/DIABLO,and reduces the mito-chondrial leakage of cytochrome C and smac/DIABLO. SCARABELLI TM,STEPHANOU A,PASINI E,et al. Journal of the American College of Cardiology . 2004

[17] M inocyc linetreatm ent reduces delayed oligodendrocyte death,attenuates ax-onal d ieback,and improves functional outcom e after sp inalcord in jury. STIRLING D P,KHODARAHM IK,LIU J,et al. Neurosc i . 2004

[18] Exces-sive m atrix m etalloprote inase activity in d iabetes:inh ib ition bytetracyc line analogues w ith zinc reactivity. RYAN M E,USMAN A,RAMAMURTHY N S,et al. Curr M edChem . 2001

[19] The influence of tetracyc lines on T cell activation. KLOPPENBURG M,VERWEIJ C L,M ILTENBURG A M,etal. C linExp Immunol . 1995

[20] Intracerebralhemorrhage induces m acrophage activation and m atrix m etallo-prote inases. POWER C,HENRY S,DEL B IG IO M R,et al. Annals of Neurology . 2003

[11] Minocycline blocks ni-tric oxide-induced neurotoxicity by inhibition p38 MAP kinasein rat cerebellar granule neurons. LIN S,ZHANG Y,DODEL R,et al. Neuroscience Letters . 2001

[12] M inocyc line inh ib itscaspase-independent and-dependentm itochondrial cell deathpathways in models of Huntington’s disease. WANG X,ZHU S,DROZDA M,et al. Proceedings of the National Academy of Sciences of the United States of America . 2003

[13] M inocyc line in-h ib its contusion-triggered m itochondrial cytochrom e c releaseand m itigates functional defic its after sp inal cord in jury. TENG Y D,CHO I H,ONAR IO R C,et al. Proceedings of the National Academy of Sciences of the United States of America . 2004

[14] M inocy-c line inh ib its cytochrom e c release and delays progression ofamyotroph ic lateral sc lerosis in m ice. ZHU S,STAVROVSKAYA I G,DROZDA M,et al. Nature . 2002

[15] M inocy-c line,a tetracyc line derivative,is neuroprotective against exc i-totoxic ity by inh ib iting activation and proliferation of m icroglia. TIKKA T,FIEB ICH B L,GOLDSTEINS G,et al. J Neurosc i . 2001

[16] Mi-nocycline inhibits caspase activation and reactivation,increa-ses the ratio of XIAP to smac/DIABLO,and reduces the mito-chondrial leakage of cytochrome C and smac/DIABLO. SCARABELLI TM,STEPHANOU A,PASINI E,et al. Journal of the American College of Cardiology . 2004

[17] M inocyc linetreatm ent reduces delayed oligodendrocyte death,attenuates ax-onal d ieback,and improves functional outcom e after sp inalcord in jury. STIRLING D P,KHODARAHM IK,LIU J,et al. Neurosc i . 2004

[18] Exces-sive m atrix m etalloprote inase activity in d iabetes:inh ib ition bytetracyc line analogues w ith zinc reactivity. RYAN M E,USMAN A,RAMAMURTHY N S,et al. Curr M edChem . 2001

[19] The influence of tetracyc lines on T cell activation. KLOPPENBURG M,VERWEIJ C L,M ILTENBURG A M,etal. C linExp Immunol . 1995

[20] Intracerebralhemorrhage induces m acrophage activation and m atrix m etallo-prote inases. POWER C,HENRY S,DEL B IG IO M R,et al. Annals of Neurology . 2003