血管内皮细胞凋亡研究进展

被引：21

作者：

王书乐

张志斌

机构：

[1] 江苏省无锡市中医医院中心实验室

来源：

辽宁中医药大学学报 | 2011年 / 13卷 / 03期

关键词：

血管内皮细胞; 凋亡;

D O I：

10.13194/j.jlunivtcm.2011.03.52.wangshy.070

中图分类号：

R329 [人体组织学];

学科分类号：

100107 [人体解剖与组织胚胎学（人体解剖学、组织与胚胎学）];

摘要：

凋亡诱导剂通过Fas/FasL/caspase途径、Cyt C途径、TNF-α途径及PARP途径等诱导血管内皮细胞凋亡。抗凋亡诱导剂通过干扰细胞凋亡的信号通路来抑制凋亡。中药作为广泛使用的抗凋亡药物在临床上已取得显著成效,但其部分具体的分子机制还不清楚。文章对血管内皮细胞凋亡的4条信号通路及凋亡诱导剂和抗凋亡诱导剂的研究进展作一综述。

引用

页码：50 / 53

页数：4

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