炎症反应中选择素粘附分子与配体间相互作用的研究

被引:4
作者
叶志义
全学军
机构
[1] 重庆工学院
关键词
选择素; P-选择素糖蛋白配体-1; 动力学;
D O I
10.13241/j.cnki.pmb.2006.10.037
中图分类号
R363 [病理生理学];
学科分类号
100104 ;
摘要
在炎症反应中,白细胞在内皮细胞上滚动由选择素分子与其配体分子相互作用所导致,选择素分子有3种,P选择素分子(P-selectin)、E选择素分子(E-selectin)、L选择素分子(L-selectin),选择素分子与其对应的P-选择素糖蛋白配体-1(PS- GL-1)的相互作用起着重要的作用。用等离子共振、流动腔、原子力显微镜等技术能定量分析选择素分子与其配体分子相互作用的动力学反应。
引用
收藏
页码:104 / 107
页数:4
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