MMP-2、MMP-9与脑缺血以及针刺调节作用的研究进展

被引：10

作者：

成越 ^{[1
]}

倪光夏 ^{[1
,2
]}

机构：

[1] 南京中医药大学

[2] 江苏省第二中医院

来源：

针灸临床杂志 | 2015年 / 31卷 / 06期

关键词：

脑缺血; MMP-2; MMP-9; 针刺; 综述;

D O I：

暂无

中图分类号：

R246.6 [神经精神病科];

学科分类号：

100225 [精神医学];

摘要：

缺血性脑卒中是全世界疾病中致残或致死的主要原因。研究发现基质金属蛋白酶-2(MMP-2)与基质金属蛋白酶-9(MMP-9)在缺血性脑损伤中发挥了重要的作用,其参与了血脑屏障的破坏、脑水肿及出血性转化等过程,因此抑制MMP-2、MMP-9成为治疗的关键。针刺早期介入治疗能够有效地抑制MMP-2、MMP-9,且具有安全、操作简便、经济等优点,是治疗脑缺血损伤的一种新途径。故本研究将MMP-2、MMP-9与脑缺血的关系以及针刺的治疗作用做以综述。

引用

页码：84 / 87

页数：4

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