Th17细胞和Treg细胞与变态反应性气道疾病

被引:6
作者
张杨 [1 ]
甄宏韬 [2 ]
机构
[1] 荆州市第一人民医院耳鼻咽喉头颈外科
[2] 华中科技大学同济医学院附属同济院耳鼻咽喉-头颈外科
关键词
D O I
暂无
中图分类号
R562 [气管和支气管疾病];
学科分类号
100201 [内科学];
摘要
<正>变态反应性疾病,如变应性鼻炎、哮喘和遗传性过敏症,都是由于免疫反应失调所引起的。从发现IL-17细胞因子家族以来,通过对IL-23介导的免疫病理反应的研究,证实了Th17是CD4+T细胞的一个亚群,产生IL-17细胞因子。IL-17促进趋化因子、促炎细胞因子和金属蛋白酶的表达,并刺激炎症反应及中
引用
收藏
页码:7330 / 7333
页数:4
相关论文
共 9 条
[1]
Functional Delineation and Differentiation Dynamics of Human CD4+ T Cells Expressing the FoxP3 Transcription Factor [J].
Miyara, Makoto ;
Yoshioka, Yumiko ;
Kitoh, Akihiko ;
Shima, Tomoko ;
Wing, Kajsa ;
Niwa, Akira ;
Parizot, Christophe ;
Taflin, Cecile ;
Heike, Toshio ;
Valeyre, Dominique ;
Mathian, Alexis ;
Nakahata, Tatsutoshi ;
Yamaguchi, Tomoyuki ;
Nomura, Takashi ;
Ono, Masahiro ;
Amoura, Zahir ;
Gorochov, Guy ;
Sakaguchi, Shimon .
IMMUNITY, 2009, 30 (06) :899-911
[2]
Thymopoiesis, regulatory t cells, and TCRVβ expression in thymoma with and without myasthenia gravis, and modulatory effects of steroid therapy [J].
Fattorossi, Andrea ;
Battaglia, Alessandra ;
Buzzonetti, Alexia ;
Minicuci, Giacomo ;
Riso, Raffaella ;
Peri, Laura ;
Scambia, Giovanni ;
Evoli, Amelia .
JOURNAL OF CLINICAL IMMUNOLOGY, 2008, 28 (02) :194-206
[3]
Quantitative and functional impairment of pulmonary CD4+CD25hi regulatory T cells in pediatric asthma [J].
Hartl, Dominik ;
Koller, Barbara ;
Mehlhorn, Alexander T. ;
Reinhardt, Dietrich ;
Nicolai, Thomas ;
Schendel, Dolores J. ;
Griese, Matthias ;
Krauss-Etschmann, Susanne .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2007, 119 (05) :1258-1266
[4]
TSLP: An Epithelial Cell Cytokine that Regulates T Cell Differentiation by Conditioning Dendritic Cell Maturation.[J].Yong-Jun Liu;Vasilli Soumelis;Norihiko Watanabe;Tomoki Ito;Yui-Hsi Wang;Rene de Waal Malefyt;Miyuki Omori;Baohua Zhou;Steven F. Ziegler.Annual Review of Immunology.2007, 0
[5]
Interleukin-17 family members and inflammation [J].
Kolls, JK ;
Lindén, A .
IMMUNITY, 2004, 21 (04) :467-476
[6]
Relation of CD4+CD25+ regulatory T-cell suppression of allergen-driven T-cell activation to atopic status and expression of allergic disease [J].
Ling, EM ;
Smith, T ;
Nguyen, XD ;
Pridgeon, C ;
Dallman, M ;
Arbery, J ;
Carr, VA ;
Robinson, DS .
LANCET, 2004, 363 (9409) :608-615
[7]
Herpesvirus Saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor [J].
Yao, ZB ;
Fanslow, WC ;
Seldin, MF ;
Rousseau, AM ;
Painter, SL ;
Comeau, MR ;
Cohen, JI ;
Spriggs, MK .
IMMUNITY, 1995, 3 (06) :811-821
[8]
转录因子RORC2和白细胞介素17的表达与变应性鼻炎症状关系的研究 [J].
卢汉桂 ;
彭华 ;
陈德华 ;
李添应 ;
史剑波 .
中华耳鼻咽喉头颈外科杂志, 2011, (02)
[9]
转录因子Foxp3在小鼠变应性鼻炎外周表达的实验研究 [J].
锡琳 ;
韩德民 ;
范尔钟 ;
李颖 ;
金善哲 ;
张伟 ;
张罗 .
首都医科大学学报, 2009, 30 (01) :49-53