高血糖与卒中

被引:24
作者
张丽
李焰生
机构
[1] 上海交通大学附属仁济医院神经内科
关键词
高血糖; 糖尿病; 卒中;
D O I
暂无
中图分类号
R587.1 [糖尿病]; R743.3 [急性脑血管疾病(中风)];
学科分类号
100201 [内科学]; 100204 [神经病学];
摘要
高血糖对卒中的发生和发展有着直接和间接的影响。目前认为,高血糖是卒中的独立危险因素。高血糖通过激活多元醇通路、形成糖基化终末产物、激活蛋白激酶C以及激活氨基己糖途径直接参与对细胞和血管的损伤;此外,高血糖通过脂质代谢、糖化血红蛋白和胰岛素等间接途径参与对血管的损伤。控制高血糖可有效降低卒中的发病率,改善卒中患者的预后。
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