神经及其他因子在子宫内膜异位性疾病疼痛中作用的研究进展

被引：10

作者：

刘芳

朱芝玲

机构：

[1] 复旦大学附属妇产科医院中西医结合科

来源：

复旦学报(医学版) | 2014年 / 02期

关键词：

子宫内膜异位; 子宫腺肌症; 疼痛; 痛经; 盆腔痛;

D O I：

暂无

中图分类号：

R711.71 [子宫内膜异位症];

学科分类号：

摘要：

疼痛是子宫内膜异位性疾病患者的典型症状之一,反复发作一直是治疗的难点。内膜异位性疾病疼痛产生的机制尚不明确,目前针对疼痛的治疗以非甾体类消炎药、激素类药物为主,但效果均不明显,且存在其他不良反应。为进一步加强疼痛的治疗,众多学者针对疼痛发生的相关因素如神经纤维、神经营养因子、缩宫素受体、辣椒素受体等展开研究。本文就子宫内膜异位性疾病疼痛相关因素研究现状进行阐述。

引用

页码：274 / 277

页数：4

共 17 条

[11]

Imbalance between sympathetic and sensory innervation in peritoneal endometriosis[J] . Julia Arnold,Maria L. Barcena de Arellano,Carola Rüster,Giuseppe F. Vercellino,Vito Chiantera,Achim Schneider,Sylvia Mechsner.Brain Behavior and Immunity . 2011 (1)

[12] Nerve fibers in ovarian endometriomas [J].

Tokushige, Natsuko ;

Russell, Peter ;

Black, Kirsten ;

Barrera, Hector ;

Dubinovsky, Sylvia ;

Markham, Robert ;

Fraser, Ian S. .

FERTILITY AND STERILITY, 2010, 94 (05) :1944-1947

[13] Immunoreactivity of oxytocin receptor and transient receptor potential vanilloid type 1 and its correlation with dysmenorrhea in adenomyosis [J].

Nie, Jichan ;

Liu, Xishi ;

Guo, Sun-Wei .

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2010, 202 (04) :346.e1-346.e8

[14] A pilot study to evaluate the clinical relevance of endometriosis-associated nerve fibers in peritoneal endometriotic lesions [J].

Mechsner, Sylvia ;

Kaiser, Andrea ;

Kopf, Andreas ;

Gericke, Christine ;

Ebert, Andreas ;

Bartley, Julia .

FERTILITY AND STERILITY, 2009, 92 (06) :1856-1861

[15] Different types of small nerve fibers in eutopic endometrium and myometrium in women with endometriosis [J].

Tokushige, Natsuko ;

Markham, Robert ;

Russell, Peter ;

Fraser, Ian S. .

FERTILITY AND STERILITY, 2007, 88 (04) :795-803

[16]

Growth-associated protein 43–positive sensory nerve fibers accompanied by immature vessels are located in or near peritoneal endometriotic lesions[J] . Sylvia Mechsner,Jessica Schwarz,Johanna Thode,Christoph Loddenkemper,David S. Salomon,Andreas D. Ebert.Fertility and Sterility . 2007 (3)

[17] Haptoglobin expression by shed endometrial tissue fragments found in peritoneal fluid [J].

Sharpe-Timms, KL .

FERTILITY AND STERILITY, 2005, 84 (01) :22-30

← 1 2 →