共 8 条
依达拉奉联合奥扎格雷钠治疗急性脑梗死的疗效及对血清CAT、MDA及SOD的影响
被引:34
作者:

刘东起
论文数: 0 引用数: 0
h-index: 0
机构: 河北省河间市人民医院
机构:
[1] 河北省河间市人民医院
来源:
关键词:
急性脑梗死;
依达拉奉;
奥扎格雷钠;
过氧化氢酶;
丙二醛;
超氧化物歧化酶;
D O I:
暂无
中图分类号:
R743.3 [急性脑血管疾病(中风)];
学科分类号:
摘要:
目的探析依达拉奉联合奥扎格雷钠治疗急性脑梗死的临床疗效及对血清过氧化氢酶(CAT)、丙二醛(MDA)及超氧化物歧化酶(SOD)的影响。方法选择112例急性脑梗死患者以随机数字表法分为A组与B组。2组均予以常规治疗,在此基础上A组予以依达拉奉联合奥扎格雷钠治疗,B组单用依达拉奉治疗。评估治疗前后对2组神经功能缺损评分(NIHSS)及卒中量表评分(CSS),测定2组血清CAT、MDA及SOD含量。结果治疗后10 d 2组CSS评分与NIHSS评分均有显著改善(P均<0.05),且A组改善更加显著(P均<0.05);治疗后A组血清SOD水平显著上升(P<0.05),B组明显降低(P<0.05),A组显著高于B组(P<0.05);治疗后2组血清CAT水平均明显提升(P均<0.05),A组提升更为明显(P<0.05);治疗后A组血清MDA水平明显降低(P<0.05),B组显著升高(P<0.05),A组显著低于B组(P<0.05)。结论依达拉奉联合奥扎格雷钠能够减轻脑水肿,清除自由基,保护CAT,减轻脑损伤,改善患者预后。
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页码:3480 / 3482
页数:3
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