PAI-1及其在血栓形成中的作用

[1] Five frequent polymorphismsof plasminogen activator inhibitor 1 gene :lack of association betweengenotypes , P A Iactivity and triglyceride levels in a healthy population. Henry M,Chomiki N,Scarabin P Y,et al. Arteriosclerosis . 1997

[2] Atherosclerosis[P]. DONG CHUNMING;GOLDSCHMIDT PASCAL J.中国专利:US2008095751A1,2008-04-24

[3] Changes in plasma levels of t P A, P A I1 and t P A P A I1 complex in patients with cerebrovascularthrombosis infused with t P A. Takada A,Takada Y,Urano T,et al. Thrombosis Research . 1990

[4] Verylowdensity lipoproteinresponse element in the promoter region of the human plasminogen activator inhibitor1 gene implicated in the impaired fibrinolysis of hypertriglyceridemia. Eriksson P,Lennart N,Fredrik K,et al. Arteriosclerosis . 1998

[5] The two allele sequences of acom mon polymorphism in the promoter of the plasminogen activator inhibitor1 ( P A I1) gene respond differently to interleukin1 in Hep G2cells. Dawson S,Wiman B,Hamsten A,et al. Journal of Biological Chemistry . 1993

[6] Metabolic determinants arem uch more important than genetic polymorphisms in determining the P A I1 activity and antigen plasma concentrations : a family study withpart of the Stanislas cohort. Henry M,Tregouet M C,Alessi M F,et al. Arteriosclerosis . 1998

[7] P A I1 synthesis in humanhepatoma cell line Hep G2 is increased by cytokinesevidence that theliver contributes to the acute phase behaviour of P A I. De Boer J,Abbnik J,Van Mourik J,et al. Thrombosis and Haemostasis . 1991

[8] P A I1 plasma levelsin a general population without clinical evidence of atherosclerosis :relation to environmental and genetic determinants. Margaglione M,Giuseppe C,Donatella C,et al. Arteriosclerosis . 1998

[9] Analysis of risk factors for recurrentcerebral infarction. Zhang Y D,Shi J P,Li Z H,et al. J Neurol . 1998

[10] Abnormally high circulation levels of tissue plasminogen activator and plasminogen activatorinhibitor1 in patients with a history ofischemic stroke. Margaglion M,Di Minno G,Grandone E,et al. Arteriosclerosis . 1994

[1] Five frequent polymorphismsof plasminogen activator inhibitor 1 gene :lack of association betweengenotypes , P A Iactivity and triglyceride levels in a healthy population. Henry M,Chomiki N,Scarabin P Y,et al. Arteriosclerosis . 1997

[2] Atherosclerosis[P]. DONG CHUNMING;GOLDSCHMIDT PASCAL J.中国专利:US2008095751A1,2008-04-24

[3] Changes in plasma levels of t P A, P A I1 and t P A P A I1 complex in patients with cerebrovascularthrombosis infused with t P A. Takada A,Takada Y,Urano T,et al. Thrombosis Research . 1990

[4] Verylowdensity lipoproteinresponse element in the promoter region of the human plasminogen activator inhibitor1 gene implicated in the impaired fibrinolysis of hypertriglyceridemia. Eriksson P,Lennart N,Fredrik K,et al. Arteriosclerosis . 1998

[5] The two allele sequences of acom mon polymorphism in the promoter of the plasminogen activator inhibitor1 ( P A I1) gene respond differently to interleukin1 in Hep G2cells. Dawson S,Wiman B,Hamsten A,et al. Journal of Biological Chemistry . 1993

[6] Metabolic determinants arem uch more important than genetic polymorphisms in determining the P A I1 activity and antigen plasma concentrations : a family study withpart of the Stanislas cohort. Henry M,Tregouet M C,Alessi M F,et al. Arteriosclerosis . 1998

[7] P A I1 synthesis in humanhepatoma cell line Hep G2 is increased by cytokinesevidence that theliver contributes to the acute phase behaviour of P A I. De Boer J,Abbnik J,Van Mourik J,et al. Thrombosis and Haemostasis . 1991

[8] P A I1 plasma levelsin a general population without clinical evidence of atherosclerosis :relation to environmental and genetic determinants. Margaglione M,Giuseppe C,Donatella C,et al. Arteriosclerosis . 1998

[9] Analysis of risk factors for recurrentcerebral infarction. Zhang Y D,Shi J P,Li Z H,et al. J Neurol . 1998

[10] Abnormally high circulation levels of tissue plasminogen activator and plasminogen activatorinhibitor1 in patients with a history ofischemic stroke. Margaglion M,Di Minno G,Grandone E,et al. Arteriosclerosis . 1994