PAI-1及其在血栓形成中的作用

被引:20
作者
孙琦
张颖冬
机构
[1] 南京医科大学附属脑科医院神经内科
关键词
纤溶酶原激活物; 抑制剂; 血栓形成;
D O I
暂无
中图分类号
R363 [病理生理学];
学科分类号
摘要
纤溶酶原激活物抑制物 1( P A I 1) 是组织型纤溶酶原激活物(t P A) 的快速抑制物。t P A 与 P A I 1间的动态平衡对维持血浆纤维蛋白溶解系统( 简称纤溶系统) 的稳态起决定性作用。 P A I 1 水平已成为血栓形成性疾病的危险因素。文章综述了 P A I 1 理化特性、 P A I 1 基因多态性同血浆中 P A I 1 水平相关性及 P A I 1水平和血栓形成的关系。
引用
收藏
页码:218 / 221
页数:4
相关论文
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