丝裂原激活蛋白激酶相关疾病及其药物的研究进展

被引：22

作者：

张美荣

刘举

王洋

机构：

[1] 辽宁大学药学院

来源：

中国药物化学杂志 | 2014年 / 24卷 / 03期

关键词：

丝裂原激活蛋白激酶; 抗肿瘤; 心血管疾病; 炎症; 糖尿病;

D O I：

10.14142/j.cnki.cn21-1313/r.2014.03.012

中图分类号：

R97 [药品];

学科分类号：

100403 [营养与食品卫生学];

摘要：

丝裂原激活蛋白激酶(MAPK)是保证人体功能正常运行的重要物质,它在细胞增殖、分化、凋亡、应激反应、炎症反应、免疫防御等过程中发挥着重要作用,MAPK异常可导致多种疾病(癌症、炎症、神经性疾病、糖尿病和高血压等)的发生。本文对丝裂原激活蛋白激酶异常导致的相关疾病、治疗药物以及作用机制方面的研究进展进行综述。

引用

页码：231 / 240

页数：10

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