克罗恩病的药物治疗进展

被引:17
作者
王玥
姜相君
机构
[1] 山东省青岛市市立医院消化内二科
关键词
克罗恩病; 生物制剂; 药物治疗;
D O I
暂无
中图分类号
R574.62 [结肠疾病];
学科分类号
100201 [内科学];
摘要
克罗恩病是一种原因不明的非特异性炎症性肠道疾病,可累及整个消化道。研究表明克罗恩病的发病与环境、遗传、免疫等因素密切相关,且不同发病机制患者临床表现也不同,对治疗的效果也差异很大,因此目前治疗也正向提高克罗恩病药物管理及优化药物策略方向努力。传统药物治疗的目标是通过应用氨基水杨酸、抗生素、糖皮质激素、巯嘌呤、甲氨蝶呤控制宿主的免疫反应。目前生物制剂的应用及最近一些新兴的治疗方法如细胞疗法也有很好的临床应用前景。本文主要对临床应用的克罗恩病药物特点及未来可供选择的药物治疗策略进行评述。
引用
收藏
页码:26 / 30
页数:5
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