肿瘤干细胞与肿瘤微环境的相互作用

被引：5

作者：

康健豪

杨光

赵世光

机构：

[1] 哈尔滨医科大学附属第一医院神经外科

来源：

临床神经外科杂志 | 2013年 / 10卷 / 06期

关键词：

D O I：

暂无

中图分类号：

R739.41 [颅内肿瘤及脑肿瘤];

学科分类号：

100115 [医学神经生物学];

摘要：

<正>Reya等于2001年提出了"肿瘤干细胞学说",认为肿瘤干细胞(cancer stem cells,CSCs)是在肿瘤组织中存在的小部分有正常干细胞样的特点,能自我更新(self-renewal)、增殖分化(differentiation)的细胞亚群,其通过不均匀分裂(asymmetric division,ASD)方式形成两个细胞,一个维持未分化的状态,作为肿瘤干细胞保留下来;另一个分化成不同

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页码：380 / 382

页数：3

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