微重力环境下MicroRNA调控成骨细胞分化研究进展

被引：3

作者：

张扬

张西正

机构：

[1] 军事医学科学院卫生装备研究所

来源：

医用生物力学 | 2018年 / 33卷 / 03期

关键词：

微小RNA; 微重力环境; 成骨细胞; 骨代谢; 调控机制;

D O I：

10.16156/j.1004-7220.2018.03.016

中图分类号：

R329.2 [人体细胞学];

学科分类号：

100107 [人体解剖与组织胚胎学（人体解剖学、组织与胚胎学）];

摘要：

MicroRNA(miRNA)是生物学过程中基因表达的重要调控分子,但miRNA在骨组织代谢过程中发挥的重要调控作用尚未完全阐明。综述现阶段miRNA在微重力环境下对成骨细胞分化的调控作用,对miRNA的调控作用分为正负两类分别进行归纳,重点介绍不同基因的作用机制,并列举在微重力环境下对骨组织代谢有重要影响的一些miRNA分子。微重力环境下miRNA对骨组织代谢性疾病具有比较重要的调控作用,其相关研究对预防及治疗失重性骨质缺失病症意义重大。

引用

页码：285 / 290

页数：6

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