水稻基因组中抗病基因正选择方式及基因转换的研究

被引：10

作者：

季军

杨四海

田大成

机构：

[1] 南京大学生命科学学院生物系

来源：

中国农业科学 | 2007年 / 09期

关键词：

水稻; NBS-LRR; 正选择; 基因转换;

D O I：

暂无

中图分类号：

S511 [稻];

学科分类号：

0901 ;

摘要：

【目的】了解正选择压力和基因转换对水稻全基因组中NBS-LRR抗病基因家族进化的影响及二者之间的相互关系。【方法】对水稻全基因组中的NBS-LRR基因进行鉴别与分类,利用PAML和GENECONV程序分别进行正选择替代和基因转换分析。【结果】在19个组(包含89个NBS-LRR基因)中检测出了显著的正选择替换位点,且约有60%正选择位点位于LRR区域;56个基因至少参与了1次基因转换事件。同时,基因转换、正选择以及基因簇之间存在明显的相关性。在84%的参与基因转换的基因中都能检测出正选择位点,且至少有84%的发生基因转换或正选择的基因都位于基因簇中。【结论】水稻基因组中的NBS-LRR基因之间,存在着频繁的正选择替代和基因转换。

引用

页码：1856 / 1863

页数：8

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