细胞-分子生物力学研究进展

被引:35
作者
吕守芹
杨帆
龙勉
机构
[1] 中国科学院力学研究所国家微重力实验室&生物力学与生物工程中心
关键词
细胞分子生物力学; 力学-生物学耦合; 力学-化学耦合;
D O I
暂无
中图分类号
R318.01 [生物力学];
学科分类号
100103 [病原生物学];
摘要
摘要细胞-分子生物力学作为生物力学的重要分支,近三十年来在力学-生物学、力学-化学耦合等方面取得了重大进展,已成为生物力学乃至生物医学工程领域最活跃的领域,并对生物学、医学乃至农业产生了重要影响。本文介绍了细胞-分子生物力学研究领域的基本概念、科学问题和研究方法,并讨论了尚待解决的问题。
引用
收藏
页码:79 / 84
页数:6
相关论文
共 17 条
[1]
Low Spring Constant Regulates P-Selectin-PSGL-1 Bond Rupture [J].
Zhang, Yan ;
Sun, Ganyun ;
Lu, Shouqin ;
Li, Ning ;
Long, Mian .
BIOPHYSICAL JOURNAL, 2008, 95 (11) :5439-5448
[2]
Flow-induced structural transition in the β-switch region of glycoprotein Ib [J].
Chen, Zhongzhou ;
Lou, Jizhong ;
Zhu, Cheng ;
Schulten, Klaus .
BIOPHYSICAL JOURNAL, 2008, 95 (03) :1303-1313
[3]
A structure-based sliding-rebinding mechanism for catch bonds [J].
Lou, Jizhong ;
Zhu, Cheng .
BIOPHYSICAL JOURNAL, 2007, 92 (05) :1471-1485
[4]
Matrix elasticity directs stem cell lineage specification [J].
Engler, Adam J. ;
Sen, Shamik ;
Sweeney, H. Lee ;
Discher, Dennis E. .
CELL, 2006, 126 (04) :677-689
[5]
Water transport in AQP0 aquaporin: Molecular dynamics studies [J].
Han, Bong-Gyoon ;
Guliaev, Anton B. ;
Walian, Peter J. ;
Jap, Bing K. .
JOURNAL OF MOLECULAR BIOLOGY, 2006, 360 (02) :285-296
[6]
Quantifying the effects of contact duration; loading rate; and approach velocity on P-selectin–PSGL-1 interactions using AFM.[J].Shouqin Lü;Zhiyi Ye;Cheng Zhu;Mian Long.Polymer.2006, 7
[7]
Force history dependence of receptor-ligand dissociation [J].
Marshall, BT ;
Sarangapani, KK ;
Lou, JH ;
McEver, RP ;
Zhu, C .
BIOPHYSICAL JOURNAL, 2005, 88 (02) :1458-1466
[8]
Forced Dissociation of Selectin-ligand Complexes Using Steered Molecular Dynamics Simulation.[J].Shouqin L " u; and Mian Long.MCB: Molecular & Cellular Biomechanics.2005, 4
[9]
Twisting DNA: single molecule studies [J].
Charvin, G ;
Allemand, JF ;
Strick, TR ;
Bensimon, D ;
Croquette, V .
CONTEMPORARY PHYSICS, 2004, 45 (05) :383-403
[10]
Kinetic measurements of cell surface E-selectin/carbohydrate ligand interactions [J].
Long, M ;
Zhao, H ;
Huang, KS ;
Zhu, C .
ANNALS OF BIOMEDICAL ENGINEERING, 2001, 29 (11) :935-946