帕金森病脑多巴胺转运体的核素显像与综合评分量表研究

被引：2

作者：

李志强 ^{[1
]}

牛小媛 ^{[1
]}

高瑾 ^{[2
]}

机构：

[1] 山西医科大学第一医院

[2] 山西省汾阳医院

来源：

山西医药杂志 | 2007年 / 11期

关键词：

帕金森病; 脑多巴胺转运体核素显像; 帕金森病综合评分量表;

D O I：

暂无

中图分类号：

R742.5 [震颤麻痹综合征]; R817.4 [在诊断上的应用];

学科分类号：

摘要：

目的探讨帕金森病脑多巴胺转运体核素显像(DAT-SPECT)的诊断价值及其与帕金森病综合评分量表(UPDRS)评分之间的相关性。方法采用脑DAT-SPECT与UPDRS评分相结合对30例早中期帕金森病患者及10例对照组进行评定。结果DAT特异性摄取于纹状体区浓集;PD患者纹状体区脑DAT特异性摄取与对照组相比明显减少,差异有统计学意义(P<0·01);PD患者脑DAT特异性摄取与UPDRS相关因素分析可见:PD患者纹状体区DAT特异性摄取率与患者运动功能评分呈可疑负相关(P=0·0895)。结论PD患者DAT-SPECT为诊断PD提供依据,并可作为判断病情和预后的标志。

引用

页码：963 / 965

页数：3

共 19 条

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