多氯联苯内分泌干扰作用及机理研究进展

被引：27

作者：

周景明

秦占芬

丛琳

徐晓白

不详

机构：

[1] 中国科学院生态环境研究中心

[2] 中国科学院生态环境研究中心北京

[3] 北京

来源：

科学通报 | 2004年 / 01期

关键词：

多氯联苯; 内分泌干扰物; 雌激素干扰物; 雄激素干扰物; 甲状腺激素干扰物;

D O I：

暂无

中图分类号：

Q45 [内分泌生理学];

学科分类号：

071003 ;

摘要：

环境内分泌干扰物是近年认识到的一类严重危害人和动物的生殖和免疫功能的环境污染物,多氯联苯(PCBs)既是持久性有机污染物,又是典型的内分泌干扰物,单个PCB同类物、PCB商品混合物以及PCB的代谢产物都具有内分泌干扰活性,可从激素的合成、转运、结合、代谢和反馈调节等多层面干扰雌/雄激素系统、甲状腺激素系统等多个内分泌系统的功能.本文详细评述了PCBs内分泌干扰活性及其机理研究的新进展,并提出了今后应加强研究的几个主要方面.

引用

页码：34 / 39

页数：6

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