尿酸性肾结石发病机制的研究进展

被引:20
作者
许金梅
唐莹莹
郭敏
李明
赵青松
陈娟
成志锋
机构
[1] 哈尔滨医科大学附属第四医院内分泌科
关键词
尿酸性肾结石; 痛风; ZNF365基因; 代谢综合征;
D O I
暂无
中图分类号
R589.7 [嘌呤(Purine)代谢障碍]; R692.4 [肾结石];
学科分类号
100201 [内科学]; 100221 [泌尿外科学];
摘要
近年来尿酸性肾结石的发病率明显升高,并且与许多疾病都具有关联性。因此对于尿酸性肾结石的研究是十分必要的。目前已有大量关于尿酸性肾结石病发病机制的研究,国内外公认的导致尿酸性肾结石发病的危险因素主要包括高尿酸尿症、低尿量以及持续低尿液p H值等。近期研究发现ZNF365基因与尿酸性肾结石的形成密切相关,还有研究表明代谢综合征与尿酸性肾结石形成也密切相关。因此为尿酸性肾结石的发病机制以及治疗都带来了重要线索。本文将对尿酸性肾结石的发病机制进行一个系统的概述。
引用
收藏
页码:165 / 168
页数:4
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