干细胞治疗溃疡性结肠炎概述

被引:11
作者
孙荔
孙涛
朱文娅
机构
[1] 中国人民解放军海军总医院消化内科
关键词
干细胞; 溃疡性结肠炎; 治疗; 间充质干细胞; 造血干细胞;
D O I
暂无
中图分类号
R574.62 [结肠疾病];
学科分类号
100201 [内科学];
摘要
溃疡性结肠炎(ulcerative colitis,UC)是一类病程迁延、反复发作、并发症多的慢性非特异性疾病,并且随着病程的发展,其并发症及癌变率逐渐上升,严重威胁患者的身心健康。而干细胞的再生、多向分化、免疫等特性使其在治疗溃疡性结肠炎方面成为研究热点之一,本文就常用造血干细胞及间充质干细胞在UC中的治疗,及可能的作用机制进行回顾性概述。
引用
收藏
页码:1409 / 1411
页数:3
相关论文
共 14 条
[1]
Inflammatory colonic carcinogenesis: A review on pathogenesis and immunosurveillance mechanisms in ulcerative colitis [J].
Scarpa, Marco ;
Castagliuolo, Ignazio ;
Castoro, Carlo ;
Pozza, Anna ;
Scarpa, Melania ;
Kotsafti, Andromachi ;
Angriman, Imerio .
WORLD JOURNAL OF GASTROENTEROLOGY, 2014, 20 (22) :6774-6785
[2]
5-氨基水杨酸维持治疗溃疡性结肠炎114例.[J].沈姞;李俊霞;王化虹;李懿璇;田雨;刘新光;.世界华人消化杂志.2011, 04
[3]
对我国炎症性肠病诊断治疗规范的共识意见 [J].
欧阳钦 ;
胡品津 ;
钱家鸣 ;
郑家驹 ;
胡仁伟 .
胃肠病学, 2007, (08) :488-495
[4]
近15年我国炎症性肠病文献分析 [J].
胡仁伟 ;
欧阳钦 ;
陈曦 ;
常玉英 ;
白爱平 ;
王瑞华 ;
张虎 .
胃肠病学, 2007, (02) :74-77
[5]
Intestinal Stem Cells and Their Defining Niche.[J].David Wei-Min Tan;Nick Barker.Current Topics in Developmental Biology.2014,
[6]
Bone marrow mesenchymal stem cells ameliorate colitis-associated tumorigenesis in mice [J].
Chen, Zexian ;
He, Xiaowen ;
He, Xiaosheng ;
Chen, Xiuting ;
Lin, Xutao ;
Zou, Yifeng ;
Wu, Xiaojian ;
Lan, Ping .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2014, 450 (04) :1402-1408
[7]
Chronic ulcerative colitis and colorectal cancer [J].
Rogler, Gerhard .
CANCER LETTERS, 2014, 345 (02) :235-241
[8]
Age-related differences in presentation and course of inflammatory bowel disease: an update on the population-based literature [J].
Duricova, Dana ;
Burisch, Johan ;
Jess, Tine ;
Gower-Rousseau, Corinne ;
Lakatos, Peter L. .
JOURNAL OF CROHNS & COLITIS, 2014, 8 (11) :1351-1361
[9]
Systematic review with meta-analysis: the declining risk of colorectal cancer in ulcerative colitis [J].
Castano-Milla, C. ;
Chaparro, M. ;
Gisbert, J. P. .
ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 2014, 39 (07) :645-659
[10]
Progression of inflammatory bowel disease in China [J].
Wang, Yu Fang ;
Ouyang, Qin ;
Hu, Ren Wei .
JOURNAL OF DIGESTIVE DISEASES, 2010, 11 (02) :76-82