β淀粉样蛋白的神经毒性作用及治疗研究进展

被引:4
作者
向诗琪
陈萍
机构
[1] 重庆医科大学附属第一医院麻醉科
关键词
β-淀粉样蛋白; 神经毒性; 药物治疗;
D O I
10.16507/j.issn.1006-6055.2012.06.034
中图分类号
R749.16 [];
学科分类号
100203 ;
摘要
β-淀粉样蛋白(beta-amyloid protein,Aβ)的产生和清除失衡,导致其在脑内异常聚集,是引发神经退行性疾病如阿尔兹海默病(alzheimer's disease,AD)的关键因素之一。目前研究还发现,全身麻醉药也可以通过增加脑组织中Aβ的表达,引起认知功能障碍。本文将对Aβ的产生、Aβ损害神经功能的具体机制及治疗Aβ神经毒性药物的最新研究进展进行综述。
引用
收藏
页码:993 / 995
页数:3
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