规范化开展以外科治疗为主的肝癌多学科综合治疗

被引:11
作者
赖俊雄
刘晓欣
刘允怡
机构
[1] 香港中文大学医学院
关键词
肝癌; 肝切除; 肝脏移植; 多学科综合治疗;
D O I
暂无
中图分类号
R735.7 [肝肿瘤];
学科分类号
100112 [医学生物化学与分子生物学];
摘要
到目前为止,手术仍然是肝癌根治性治疗的主要手段。以外科治疗为主的综合治疗,日益受到重视。其含义主要包括3个方面:(1)可切除肝癌在术前、术后行综合治疗,以减少肝癌复发和转移;(2)不可手术切除肝癌病人的综合治疗,目的是二期切除;(3)肝移植前辅助治疗,目的是控制肿瘤进展,增长等候供肝的时间。由于国内外已发表的研究在数量和质量上均存在局限性,所有综合治疗的报道均是小样本、非随机对照研究,无法给临床选择提供可靠的证据。尚有待开展大样本、高质量的多中心随机对照研究,并通过长期随访评估其远期疗效。由于没有足够的证据作治疗的规范化,临床医生可以根据目前仅有的证据,结合病人的具体情况来综合评估病情,选择最佳的治疗方式。新的治疗只应通过恰当设计的研究作测试其疗效。综合治疗补充手术治疗的不足,增加外科手术切除机会与减少术后复发转移等方向的研究,是今后肝癌外科领域的重要任务。
引用
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页码:719 / 722
页数:4
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