Graves病发病机制新进展

被引：55

作者：

郑慧娟

魏璠

魏军平

机构：

[1] 中国中医科学院广安门医院内分泌科

来源：

中国免疫学杂志 | 2017年 / 33卷 / 04期

关键词：

D O I：

暂无

中图分类号：

R581 [甲状腺疾病];

学科分类号：

100201 [内科学];

摘要：

<正>Graves病（Graves disease,GD）又称毒性弥漫性甲状腺肿,是针对甲状腺滤泡细胞膜上促甲状腺激素受体（Thyroid stimulating hormone receptor,TSHR）产生的抗体（TRAb）所引起的一种自身免疫性疾病,是引起甲亢最常见的原因,每年发病率约为20～30/1 000 000,约有3%的女性和0.5%的男性患病,一般集中在30～60年龄段[1]。目前GD发病机制尚未完全阐明,近年来有大量关于表观遗传、环

引用

页码：621 / 624

页数：4

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