PI3K-Akt信号通路与心肌保护

被引：11

作者：

唐莹

刘金东

机构：

[1] 江苏省麻醉医学研究所重点实验室

来源：

医学综述 | 2009年 / 15卷 / 10期

关键词：

磷酯酰肌醇-3激-酶-丝氨酸/苏氨酸激酶; 心肌保护; 心肌缺血/再灌注损伤;

D O I：

暂无

中图分类号：

R541 [心脏疾病];

学科分类号：

摘要：

越来越多的研究表明,药物及非药物手段可以在再灌注之初通过活化磷酯酰肌醇-3-激酶-丝氨酸/苏氨酸激酶(PI3K-Akt)这一共同通路,发挥提高心肌功能和促进细胞存活的重要作用。本文对PI3K、Akt、下游靶点、效应器在缺血/再灌注中的作用进行综述,阐明PI3K-Akt信号通路的主动保护效应在心肌保护中的重要性。

引用

页码：1470 / 1473

页数：4

共 20 条

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