IL-23/IL-17炎症轴在类风湿关节炎发病机制中的研究进展

被引：28

作者：

余黄合 ^{[1
,2
]}

魏艳霞 ^{[1
]}

林也 ^{[1
]}

王莘智 ^{[1
]}

李如意 ^{[1
,2
]}

李鑫 ^{[1
]}

曾嵘 ^{[2
]}

蔡雄 ^{[1
,3
]}

机构：

[1] 湖南中医药大学中医诊断学湖南省重点实验室

[2] 湖南中医药大学药学院

[3] 湖南中医药大学中医方证转化医学研究湖南省高校重点实验室

来源：

中国医药导报 | 2016年 / 13卷 / 31期

关键词：

类风湿关节炎; 发病机制; IL-23/IL-17炎症轴; 治疗药物;

D O I：

暂无

中图分类号：

R593.22 [类风湿性关节炎];

学科分类号：

100201 [内科学];

摘要：

类风湿关节炎是一种以关节滑膜慢性炎症、软骨和骨的破坏为主要表现的系统性自身免疫性疾病,其发病机制复杂,研究发现该疾病的发生、发展与IL-23/IL-17炎症轴有密切关系,本文将IL-23、IL-17及IL-23/IL-17炎症轴对类风湿关节炎发病机制的影响及与该轴相关的治疗药物予以综述,为开发针对该靶点治疗类风湿关节炎的药物提供新思路。

引用

页码：37 / 41

页数：5

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