七氟烷对缺血性脑损伤保护机制的研究进展

被引：7

作者：

纪维

夏德国

机构：

[1] 苏北人民医院麻醉科

来源：

中华临床医师杂志(电子版) | 2015年 / 9卷 / 24期

关键词：

麻醉药,吸入; 脑缺血;

D O I：

暂无

中图分类号：

R743.3 [急性脑血管疾病（中风）];

学科分类号：

100204 [神经病学];

摘要：

吸入性麻醉药七氟烷被广泛应用于颅脑外科麻醉。近年来,七氟烷对于缺血性脑损伤的保护作用引起了研究者们的重视。七氟烷可能通过抑制线粒体膜通透性转换孔开放、激活ATP敏感钾离子通道、消除氧自由基、抑制钙离子超载等多位点、多途径交互作用来发挥神经保护作用,本文总结了近年来七氟烷对缺血性脑损伤保护的研究,对其相关机制作一综述,为全面揭示脑保护机制提供研究思路,并为临床麻醉用药提供理论依据。

引用

页码：4712 / 4715

页数：4

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