乙型肝炎分子流行病学研究进展

被引：6

作者：

纪惠玲

郭燕

郑能雄

机构：

[1] 福州市疾病预防控制中心

来源：

国际免疫学杂志 | 2008年 / 01期

关键词：

乙型肝炎病毒; HBV定量; HBV基因分型; HBV基因变异; HBV易感性;

D O I：

暂无

中图分类号：

R512.62 [];

学科分类号：

100401 ;

摘要：

乙肝的分子流行病学是运用先进的分子生物学技术研究乙肝流行病学的诸多问题,能够进一步从分子水平阐明乙型肝炎病毒感染的病因、致病过程及发病机制,对于疾病早期诊断、传染性的评估、病情的预测、抗病毒药物疗效的观察、疾病发展进程的监测和乙肝感染自然史的研究等方面均有重要的指导意义。针对近几年乙肝分子流行病学研究的几个热点即乙型肝炎病毒的检测、基因分型、基因系统进化分析、基因变异、基因多态性的研究进展作一回顾。虽然近年来该领域的研究迅速增多,但多数仍处于探索阶段,乙肝病毒感染、清除等诸多机制的研究仍任重而道远。

引用

页码：55 / 59

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