从肿瘤微环境正常化探讨活血化瘀法及除痰散结法在肿瘤治疗中的机制

被引:34
作者
唐振豪 [1 ]
兰聪颖 [1 ]
林丽珠 [2 ]
机构
[1] 广州中医药大学
[2] 广州中医药大学第一附属医院
关键词
肿瘤微环境; 肿瘤治疗; 活血化瘀; 除痰散结;
D O I
10.13359/j.cnki.gzxbtcm.2019.07.032
中图分类号
R273 [中医肿瘤科];
学科分类号
100502 [中医临床基础];
摘要
肿瘤微环境由间质细胞、细胞外基质及肿瘤血管构成,是肿瘤细胞赖以存活、生长及增殖的环境。肿瘤微环境具有乏氧、高乳酸浓度及低pH值、高组织间隙液压及高固体压力4个特性;促进肿瘤微环境正常化应成为常规的现代肿瘤治疗策略。中医活血化瘀法及除痰散结法治疗肿瘤的机制即为通过促进肿瘤血管正常化及减少细胞外基质来实现肿瘤微环境正常化。
引用
收藏
页码:1091 / 1098
页数:8
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