高血压患者外周动脉疾病与血尿酸水平关系的研究

被引:2
作者
顾剑云 [1 ]
胡大一 [1 ]
魏毅东 [1 ]
李觉 [2 ]
郑黎强 [2 ]
机构
[1] 同济大学心肺血管中心
[2] 上海同济大学医学院流行病学教研室
关键词
外周动脉疾病; 高血压; 动脉粥样硬化; 踝臂指数;
D O I
暂无
中图分类号
R544.1 [高血压];
学科分类号
1002 ; 100201 ;
摘要
目的比较高血压合并外周动脉疾病与高血压不合并外周动脉疾病患者的血尿酸水平,探讨高血压患者外周动脉疾病与血尿酸水平的关系。方法北京及上海地区医院住院的4 415例明确诊断原发性高血压患者为研究对象,测量他们的踝臂指数,踝臂指数<0.90者诊断为外周动脉疾病(peripheral arterial disease,PAD)。将研究对象分为PAD组1 221例,非PAD组3 194例,测定其血脂及尿酸水平,对结果进行统计学处理。结果PAD组血尿酸水平(349.43±125.99μmol/L)明显高于非PAD组(327.24±110.29μmol/L)(P≤0.01),经logistic回归分析,显示尿酸水平与PAD相关(P≤0.01)。结论血尿酸水平和糖尿病史、吸烟史、性别一样是高血压患者合并外周动脉疾病的危险因素。
引用
收藏
页码:46 / 49
页数:4
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