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Modulation of STAT-3 in rheumatoid synovial T cells suppresses Th17 differentiation and increases the proportion of treg cells
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Th17 cells are restrained by Treg cells via the inhibition of interleukin‐6 in patients with rheumatoid arthritis responding to anti–tumor necrosis factor antibody therapy.[J].Jenny L. McGovern;Dao X. Nguyen;Clare A. Notley;Claudia Mauri;David A. Isenberg;Michael R. Ehrenstein.Arthritis & Rheumatism.2012, 10
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Different effects of biological drugs in rheumatoid arthritis.[J].Fabiola Atzeni;Maurizio Benucci;Salvatore Sallì;Sara Bongiovanni;Laura Boccassini;Piercarlo Sarzi-Puttini.Autoimmunity Reviews.2012,
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LY2439821; a humanized anti–interleukin‐17 monoclonal antibody; in the treatment of patients with rheumatoid arthritis: A phase I randomized; double‐blind; placebo‐controlled; proof‐of‐concept study.[J].M. C.Genovese;F.Van den Bosch;S. A.Roberson;S.Bojin;I. M.Biagini;PeterRyan;J.Sloan‐Lancaster.Arthritis & Rheumatism.2010, 4
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CD4<sup>+</sup> CD25<sup>+</sup> T cells with the phenotypic and functional characteristics of regulatory T cells are enriched in the synovial fluid of patients with rheumatoid arthritis.[J].M. Möttönen;J. Heikkinen;L. Mustonen;P. Isomäki;R. Luukkainen;O. Lassila.Clinical & Experimental Immunology.2005, 2
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CD4+CD25+ regulatory T cells in rheumatoid arthritis - Differences in the presence, phenotype, and function between peripheral blood and synovial fluid
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2004, 50 (09)
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