奥扎格雷钠治疗出血性脑梗死的临床观察

被引：3

作者：

陈育华

谢静

马博

钱卫东

屈洪党

机构：

[1] 安徽省蚌埠医学院第一附属医院神经内科

来源：

中华全科医学 | 2010年 / 8卷 / 11期

关键词：

脑梗死出血性转化; 奥扎格雷钠; 血小板;

D O I：

10.16766/j.cnki.issn.1674-4152.2010.11.068

中图分类号：

R743.33 [脑栓塞];

学科分类号：

摘要：

目的探讨奥扎格雷钠治疗出血性脑梗死(HI)的临床疗效及安全性。方法将入选的39例HI患者随机分为奥扎格雷钠治疗组20例和对照组19例,治疗组予奥扎格雷80mg加入5%的葡萄糖水静脉滴注,2次/d,其他治疗同对照组。对照组给予中性治疗。两组治疗时间均为14d。各组治疗前后分别进行神经功能障碍评分及疗效分析,监测凝血功能和血小板。结果治疗期间两组患者均无再出血发生;治疗组无再梗死发生,对照组有2例再梗死发生;治疗组治疗后NIHSS均值低于对照组(P<0.05),总显效率和总有效率高于对照组(P<0.05)。结论奥扎格雷治疗HI是安全有效的。

引用

页码：1360 / 1361

页数：2

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