蛋白酶体抑制剂的研究进展

被引：4

作者：

牟科

付翌秋

徐萍

机构：

[1] 北京大学药学院药物化学系

来源：

国际药学研究杂志 | 2009年 / 36卷 / 05期

关键词：

蛋白酶体; 蛋白酶体,抑制剂; 抗肿瘤药物;

D O I：

10.13220/j.cnki.jipr.2009.05.011

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

作为体内蛋白质降解的途径之一,蛋白酶体具有非常重要的生理作用,并与多种疾病密切相关。抑制蛋白酶体的功能已经成为肿瘤治疗的又一有前景的新途径,并受到越来越多的关注。本文对蛋白酶体的组成结构、病理生理作用和现有抑制剂进行归纳总结。

引用

收藏

页码：348 / 354

页数：7

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