Toll样受体研究进展

被引:17
作者
张琪 [1 ]
周兵 [2 ]
机构
[1] 首都医科大学附属北京同仁医院
[2] 首都医科大学附属北京同仁医院耳鼻咽喉头颈外科 耳鼻咽喉头颈科学教育部重点实验室(首都医科大学)
关键词
免疫,天然(Immunity,Innate); Toll样受体(Toll-like Receptors);
D O I
暂无
中图分类号
R392 [医学免疫学];
学科分类号
100108 [医学免疫学];
摘要
机体的免疫系统承担着抵御外界病原体入侵这一重任。Toll样受体作为天然免疫和获得性免疫的重要门户,是植物、昆虫和哺乳类动物等宿主进行免疫防御的监视器,它的重要作用已逐渐为人们所认识。自Toll样受体发现至今已有十余年,有关的结构、分布、配体及介导的信号通路已有初步的研究,本文就Toll样受体的最新进展进行综述。
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