同型半胱氨酸与心脑血管疾病相关性研究进展

被引:66
作者
刘君
万云高
孙志媛
徐东
机构
[1] 首都医科大学宣武医院心脏科
关键词
心脑血管疾病; 内皮细胞; Hcy; 同型半胱氨酸; 急性冠状动脉综合征; 依那普利叶酸片; 血浆; 独立危险因素; 甲基供体; 动脉粥样硬化性; 相关性研究;
D O I
暂无
中图分类号
R54 [心脏、血管(循环系)疾病]; R743 [脑血管疾病];
学科分类号
1002 ; 100201 ;
摘要
<正>心脑血管疾病在世界范围内都是威胁人类健康的主要疾病之一。而动脉粥样硬化(atherosclerosis,AS)是此类疾病重要的病理基础。能导致AS的除了传统危险因素如吸烟、高血压、高脂血症等之外,近年来大量研究发现同型半胱氨
引用
收藏
页码:116 / 120
页数:5
相关论文
共 19 条
[11]  
Pronounced association of elevated serum homocysteine with stroke in subgroups of individuals: A nationwide study[J] . Amytis Towfighi,Daniela Markovic,Bruce Ovbiagele.Journal of the Neurological Sciences . 2010 (1)
[12]  
Gene polymorphisms and risk of adult early-onset ischemic stroke: A meta-analysis[J] . Xiao-Yu Xin,Yan-Yan Song,Jian-Fang Ma,Cai-Ni Fan,Jian-Qing Ding,Guo-Yuan Yang,Sheng-Di Chen.Thrombosis Research . 2009 (5)
[13]   Relationship of homocysteine with other risk factors and outcome of ischemic stroke [J].
Kalita, Jayantee ;
Kumar, Gyanendra ;
Bansal, Vikas ;
Misra, Usha Kant .
CLINICAL NEUROLOGY AND NEUROSURGERY, 2009, 111 (04) :364-367
[14]   Ethnicity Does Not Affect the Homocysteine-Lowering Effect of B-Vitamin Therapy in Singaporean Stroke Patients [J].
Kasiman, Katherine ;
Eikelboom, John W. ;
Hankey, Graeme J. ;
Lee, Samantha P. -K. ;
Lim, Joanna P. -Z. ;
Lee, Jasinda H. -Q. ;
Chang, Hui-Meng ;
Wong, Meng-Cheong ;
Chen, Christopher P. L. -H. .
STROKE, 2009, 40 (06) :2209-2211
[15]   Homocystinuria due to cystathionine beta synthase deficiency [J].
Rao, T. Narayana ;
Radhakrishna, K. ;
Rao, T. S. Mohana ;
Guruprasad, P. ;
Ahmed, Kamal .
INDIAN JOURNAL OF DERMATOLOGY VENEREOLOGY & LEPROLOGY, 2008, 74 (04) :375-378
[16]  
Homocysteine And Cardiovascular Disease: Evidence On Causality From A Meta-Analysis[J] . David S. Wald,Malcolm Law,Joan K. Morris.BMJ: British Medical Journal . 2002 (7374)
[17]  
Stroke is More Common than Myocardial Infarction in Hypertension: Analysis based on 11 Major Randomized Intervention Trials[J] . Sverre E. Kjeldsen,Stevo Julius,Thomas Hedner,Lennart Hansson.Blood Pressure . 2001 (4)
[18]  
Polygenic influence on plasma homocysteine: association of two prevalent mutations, the 844ins68 of cystathionine β-synthase and A 2756 G of methionine synthase, with lowered plasma homocysteine levels[J] . Michael Y Tsai,Michelle Bignell,Feng Yang,Barry G Welge,Kevin J Graham,Naomi Q Hanson.Atherosclerosis . 2000 (1)
[19]   Homocysteine as a novel risk factor for atherosclerosis [J].
Guthikonda, S ;
Haynes, WG .
CURRENT OPINION IN CARDIOLOGY, 1999, 14 (04) :283-291