心源性脑栓塞和大动脉粥样硬化性脑梗死患者自发性出血性转化的发生及相关因素分析

被引:15
作者
肖美娟 [1 ]
殷为勇 [1 ]
叶祖森 [1 ]
曹云刚 [2 ]
邵蓓 [1 ]
韩钊 [2 ]
机构
[1] 温州医科大学附属第一医院神经内一科
[2] 温州医科大学附属第二医院神经内科
关键词
脑梗塞; 自发性出血性转化; 危险因素;
D O I
暂无
中图分类号
R743.3 [急性脑血管疾病(中风)];
学科分类号
100204 [神经病学];
摘要
收集150例心源性脑栓塞(CE)和370例大动脉性粥样硬化性脑梗死(LAA)患者的临床资料, 分析自发性出血性转化(HT)的发生及危险因素。结果显示, CE后HT发生率为29.3%, 显著高于LAA的9.7%(P<0.05);梗死面积大、入院时美国国立卫生院神经功能缺损评分(NIHSS)高、随机血糖水平是影响CE患者HT的危险因素(OR值分别为3.92、2.96、1.45);梗死面积大、低水平LDL-C、入院时NIHSS高是LAA患者HT的独立危险因素(OR值分别为4.86、2.42、1.42)。提示HT在CE患者后更常见;CE和LAA患者HT的危险因素不完全相同。
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