基因打靶技术的研究进展

被引：6

作者：

张丽娜

刘国安

杨红

机构：

[1] 西北师范大学生命科学学院

来源：

生物技术通报 | 2010年 / 09期

关键词：

基因打靶; DNA同源重组; 胚胎干细胞;

D O I：

10.13560/j.cnki.biotech.bull.1985.2010.09.008

中图分类号：

Q78 [基因工程（遗传工程）];

学科分类号：

071007 ; 0836 ; 090102 ;

摘要：

基因打靶技术是20世纪80年代发展起来的新技术,是一种利用DNA同源重组原理和胚胎干细胞(ES细胞)技术按定向组合的方式改变生物活体遗传信息的试验手段,具有广阔的应用前景。对基因打靶技术原理、步骤、条件性基因打靶以及应用进行综述。

引用

页码：51 / 55

页数：5

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