基因打靶技术的研究进展

被引:6
作者
张丽娜
刘国安
杨红
机构
[1] 西北师范大学生命科学学院
关键词
基因打靶; DNA同源重组; 胚胎干细胞;
D O I
10.13560/j.cnki.biotech.bull.1985.2010.09.008
中图分类号
Q78 [基因工程(遗传工程)];
学科分类号
071007 ; 0836 ; 090102 ;
摘要
基因打靶技术是20世纪80年代发展起来的新技术,是一种利用DNA同源重组原理和胚胎干细胞(ES细胞)技术按定向组合的方式改变生物活体遗传信息的试验手段,具有广阔的应用前景。对基因打靶技术原理、步骤、条件性基因打靶以及应用进行综述。
引用
收藏
页码:51 / 55
页数:5
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