肠碱性磷酸酶在肠屏障中作用的研究进展

被引:23
作者
毕景成
王新颖
黎介寿
机构
[1] 南京大学医学院附属金陵医院(南京军区南京总医院)解放军普通外科研究所
关键词
肠碱性磷酸酶; 肠屏障; 综述文献;
D O I
10.16151/j.1007-810x.2015.04.016
中图分类号
R57 [消化系及腹部疾病];
学科分类号
100201 [内科学];
摘要
肠碱性磷酸酶(IAP)是一种经糖基磷脂酰肌醇键锚定于肠上皮细胞顶膜上的糖蛋白,在肠黏膜屏障的维护中发挥着重要作用,包括调节十二指肠表面p H值、解除脂多糖(LPS)和游离核苷酸的毒性、抑制肠道炎性反应、调节肠道菌群等。以下就近年来IAP在肠屏障中的作用研究进展作一综述。
引用
收藏
页码:244 / 247
页数:4
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